Cheapest one-way flights from Santa Cruz to Madrid in May from $594

AirHint found the following cheapest one-way flights from Santa Cruz (VVI) to Madrid (MAD) in May 2026 (see full year).

One-Way flights

18 May Boliviana de Aviacion direct
21 May Boliviana de Aviacion direct
19 May Air Europa direct
28 May Air Europa direct
07 May Air Europa direct
14 May Air Europa direct
16 May Iberia direct
02 May Iberia direct
06 May Boliviana de Aviacion
17 May Boliviana de Aviacion

Also check the deals for return flights from Santa Cruz to Madrid in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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