AirHint found the following cheapest return flights from Amsterdam (AMS) to Madrid (MAD) in October 2025 (see full year).

Return flights

02 Oct - 06 Oct	Iberia	direct
01 Oct - 04 Oct	Iberia	direct
03 Oct - 06 Oct	Iberia	direct
04 Oct - 07 Oct	Vueling Airlines
14 Oct - 20 Oct	Vueling Airlines
28 Oct - 11 Nov	Vueling Airlines
27 Oct - 03 Nov	Ryanair
07 Oct - 15 Oct	Vueling Airlines
04 Oct - 08 Oct	Vueling Airlines
30 Oct - 11 Nov	KLM	direct
26 Oct - 29 Oct	Ryanair
23 Oct - 04 Nov	easyJet
15 Oct - 20 Oct	easyJet
25 Oct - 29 Oct	Vueling Airlines
28 Oct - 11 Nov	KLM	direct
23 Oct - 03 Nov	easyJet
22 Oct - 03 Nov	easyJet
30 Oct - 06 Nov	KLM	direct
31 Oct - 03 Nov	easyJet
31 Oct - 05 Nov	easyJet

Also check the deals for one-way flights from Amsterdam to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Amsterdam to Madrid in October from $166

Return flights