AirHint found the following cheapest return flights from Amsterdam (AMS) to Santiago (SCL) in October 2025 (see full year).

Return flights

08 Oct - 29 Oct	Delta
02 Oct - 30 Oct	Delta
06 Oct - 20 Oct	Delta
16 Oct - 29 Oct	Delta
05 Oct - 24 Oct	Delta
30 Oct - 23 Nov	Delta
09 Oct - 24 Oct	Delta
15 Oct - 26 Oct	Delta
15 Oct - 24 Oct	Delta
14 Oct - 08 Nov	Delta
15 Oct - 26 Nov	Delta
09 Oct - 12 Oct	Delta
19 Oct - 26 Oct	Delta
19 Oct - 10 Nov	Delta
19 Oct - 27 Nov	Delta
23 Oct - 02 Nov	Delta
26 Oct - 29 Nov	Delta
18 Oct - 29 Nov	Air Transat

Also check the deals for one-way flights from Amsterdam to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Amsterdam to Santiago in October from $889

Return flights