AirHint found the following cheapest return flights from Amsterdam (AMS) to Santiago (SCL) in December 2025 (see full year).

Return flights

01 Dec - 08 Dec	Air Canada
16 Dec - 20 Jan	Air Canada
14 Dec - 19 Jan	Air Canada
17 Dec - 31 Jan	Air Canada
27 Dec - 17 Jan	Delta
27 Dec - 20 Jan	Delta
14 Dec - 24 Dec	Air Canada
04 Dec - 30 Dec	Air Canada
24 Dec - 21 Jan	Delta
24 Dec - 17 Jan	Delta
25 Dec - 15 Jan	Delta
25 Dec - 28 Jan	Delta
15 Dec - 15 Jan	Delta
04 Dec - 31 Dec	TAP
15 Dec - 22 Dec	Delta
01 Dec - 15 Dec	Delta
15 Dec - 28 Dec	Delta
15 Dec - 26 Dec	Delta
23 Dec - 30 Dec	Iberia
13 Dec - 23 Dec	Delta

Also check the deals for one-way flights from Amsterdam to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Amsterdam to Santiago in December from $826

Return flights