AirHint found the following cheapest return flights from Amsterdam (AMS) to Santiago (SCL) in December 2025 (see full year).

Return flights

03 Dec - 09 Dec	Delta
08 Dec - 27 Dec	Delta
08 Dec - 24 Dec	Delta
01 Dec - 08 Dec	Delta
01 Dec - 21 Jan	Delta
29 Dec - 18 Jan	Delta
29 Dec - 25 Jan	Delta
29 Dec - 21 Jan	Delta
30 Dec - 21 Jan	Delta
03 Dec - 10 Dec	Air Canada
02 Dec - 09 Dec	Delta
24 Dec - 30 Jan	Delta
27 Dec - 20 Jan	Delta
27 Dec - 15 Jan	Delta
24 Dec - 08 Jan	Air Canada
26 Dec - 07 Jan	Air Canada
06 Dec - 19 Dec	Iberia
03 Dec - 16 Dec	Iberia
01 Dec - 19 Dec	Iberia
14 Dec - 29 Dec	Iberia

Also check the deals for one-way flights from Amsterdam to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Amsterdam to Santiago in December from $886

Return flights