Cheapest return flights from Antofagasta to La Serena in December from $67

AirHint found the following cheapest return flights from Antofagasta (ANF) to La Serena (LSC) in December 2025 (see full year).

Return flights

01 Dec - 12 Dec JetSmart direct
01 Dec - 03 Dec JetSmart direct
10 Dec - 12 Dec JetSmart direct
05 Dec - 12 Dec JetSmart direct
02 Dec - 12 Dec JetSmart direct
02 Dec - 03 Dec JetSmart direct
03 Dec - 12 Dec JetSmart direct
22 Dec - 06 Jan JetSmart direct
04 Dec - 12 Dec JetSmart direct
01 Dec - 09 Dec JetSmart direct
17 Dec - 06 Jan JetSmart direct
03 Dec - 03 Dec JetSmart direct
16 Dec - 06 Jan JetSmart direct
19 Dec - 06 Jan JetSmart direct
23 Dec - 06 Jan JetSmart direct
24 Dec - 13 Jan JetSmart direct
24 Dec - 06 Jan JetSmart direct
23 Dec - 13 Jan JetSmart direct
24 Dec - 04 Jan Sky Airline direct
22 Dec - 04 Jan JetSmart

Also check the deals for one-way flights from Antofagasta to La Serena in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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