Cheapest return flights from Antofagasta to Santiago in December from $95

AirHint found the following cheapest return flights from Antofagasta (ANF) to Santiago (SCL) in December 2025 (see full year).

Return flights

29 Dec - 01 Jan LATAM Airlines Group direct
31 Dec - 15 Jan JetSmart direct
31 Dec - 16 Jan JetSmart direct
28 Dec - 01 Jan JetSmart direct
28 Dec - 15 Jan JetSmart direct
28 Dec - 16 Jan JetSmart direct
26 Dec - 29 Dec Sky Airline
28 Dec - 31 Dec JetSmart direct
31 Dec - 17 Jan JetSmart direct
31 Dec - 09 Jan JetSmart direct
31 Dec - 21 Jan JetSmart direct
31 Dec - 07 Jan JetSmart direct
26 Dec - 29 Dec Sky Airline direct
28 Dec - 30 Dec LATAM Airlines Group direct
26 Dec - 30 Dec Sky Airline
26 Dec - 31 Dec JetSmart direct
26 Dec - 30 Dec Sky Airline direct
29 Dec - 31 Dec JetSmart direct
31 Dec - 31 Dec JetSmart direct
30 Dec - 30 Dec JetSmart direct

Also check the deals for one-way flights from Antofagasta to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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