AirHint found the following cheapest return flights from Ancona (AOI) to Prague (PRG) in December 2025 (see full year).

Return flights

31 Dec - 01 Jan	Wizz Air Malta
15 Dec - 18 Dec	Ryanair
11 Dec - 13 Dec	DAT
29 Dec - 01 Jan	Wizz Air Malta
15 Dec - 19 Dec	Ryanair
06 Dec - 08 Dec	Lufthansa
31 Dec - 05 Jan	Wizz Air Malta
04 Dec - 07 Dec	DAT
31 Dec - 02 Jan	Wizz Air Malta
27 Dec - 02 Jan	Wizz Air Malta
30 Dec - 02 Jan	DAT

Also check the deals for one-way flights from Ancona to Prague in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Ancona to Prague in December from $185

Return flights