AirHint found the following cheapest return flights from Arequipa (AQP) to Santiago (SCL) in September 2025 (see full year).

Return flights

30 Sep - 06 Oct	JetSmart
18 Sep - 06 Oct	JetSmart
04 Sep - 25 Sep	JetSmart
23 Sep - 06 Oct	JetSmart
18 Sep - 25 Sep	JetSmart
04 Sep - 16 Sep	JetSmart
04 Sep - 08 Sep	JetSmart
15 Sep - 06 Oct	JetSmart
04 Sep - 20 Sep	JetSmart
23 Sep - 25 Sep	JetSmart
15 Sep - 20 Sep	LATAM Airlines Group
24 Sep - 06 Oct	JetSmart
18 Sep - 20 Sep	JetSmart
30 Sep - 08 Oct	JetSmart
15 Sep - 25 Sep	JetSmart
25 Sep - 06 Oct	JetSmart
18 Sep - 08 Oct	JetSmart
04 Sep - 15 Sep	JetSmart
23 Sep - 08 Oct	JetSmart
26 Sep - 06 Oct	JetSmart

Also check the deals for one-way flights from Arequipa to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Arequipa to Santiago in September from $244

Return flights