AirHint found the following cheapest return flights from Asuncion (ASU) to Santiago (SCL) in December 2025 (see full year).

Return flights

10 Dec - 16 Dec	JetSmart
10 Dec - 26 Dec	JetSmart
18 Dec - 26 Dec	JetSmart
11 Dec - 16 Dec	JetSmart
13 Dec - 16 Dec	JetSmart
11 Dec - 26 Dec	JetSmart
25 Dec - 15 Jan	JetSmart
31 Dec - 15 Jan	JetSmart
13 Dec - 26 Dec	JetSmart
18 Dec - 01 Jan	JetSmart
28 Dec - 15 Jan	JetSmart
18 Dec - 07 Jan	JetSmart
10 Dec - 25 Dec	JetSmart
14 Dec - 16 Dec	JetSmart
20 Dec - 26 Dec	JetSmart
13 Dec - 01 Jan	JetSmart
11 Dec - 01 Jan	JetSmart
25 Dec - 14 Jan	JetSmart
31 Dec - 14 Jan	JetSmart
20 Dec - 01 Jan	JetSmart

Also check the deals for one-way flights from Asuncion to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Asuncion to Santiago in December from $264

Return flights