AirHint found the following cheapest return flights from Asuncion (ASU) to Santiago (SCL) in September 2025 (see full year).

Return flights

09 Sep - 11 Sep	JetSmart
09 Sep - 10 Sep	JetSmart
02 Sep - 09 Sep	JetSmart
02 Sep - 08 Sep	JetSmart
02 Sep - 11 Sep	JetSmart
02 Sep - 10 Sep	JetSmart
07 Sep - 09 Sep	JetSmart
07 Sep - 08 Sep	JetSmart
07 Sep - 11 Sep	JetSmart
07 Sep - 10 Sep	JetSmart
16 Sep - 02 Oct	JetSmart
16 Sep - 01 Oct	JetSmart
11 Sep - 02 Oct	JetSmart
11 Sep - 01 Oct	JetSmart
16 Sep - 03 Oct	JetSmart

Also check the deals for one-way flights from Asuncion to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Asuncion to Santiago in September from $230

Return flights