AirHint found the following cheapest return flights from Boston (BOS) to Rome (FCO) in September 2025 (see full year).

Return flights

28 Sep - 08 Oct	TAP
23 Sep - 08 Oct	TAP
21 Sep - 03 Oct	TAP
06 Sep - 21 Sep	TAP
30 Sep - 14 Oct	Icelandair
14 Sep - 02 Oct	TAP
06 Sep - 01 Oct	TAP
08 Sep - 14 Sep	TAP
22 Sep - 30 Sep	TAP
13 Sep - 21 Sep	TAP
11 Sep - 19 Sep	TAP
11 Sep - 21 Sep	TAP
13 Sep - 20 Sep	TAP
24 Sep - 03 Oct	TAP
28 Sep - 09 Oct	Icelandair
20 Sep - 05 Oct	TAP
03 Sep - 09 Sep	TAP
24 Sep - 01 Oct	TAP
01 Sep - 10 Sep	TAP
11 Sep - 18 Sep	TAP

Also check the deals for one-way flights from Boston to Rome in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Boston to Rome in September from $364

Return flights