AirHint found the following cheapest return flights from Boston (BOS) to Istanbul (IST) in October 2025 (see full year).

Return flights

15 Oct - 17 Nov	Icelandair
25 Oct - 07 Nov	Icelandair
25 Oct - 31 Oct	Icelandair
27 Oct - 03 Nov	Iberia
19 Oct - 06 Nov	Delta
20 Oct - 06 Nov	Delta
20 Oct - 04 Nov	Delta
28 Oct - 04 Nov	Air Canada
19 Oct - 04 Nov	Delta
21 Oct - 04 Nov	Air Canada
29 Oct - 27 Nov	Delta
01 Oct - 31 Oct	Icelandair
11 Oct - 17 Oct	Icelandair
21 Oct - 28 Oct	Air Canada
05 Oct - 09 Oct	Icelandair
11 Oct - 16 Oct	TAP
04 Oct - 07 Oct	Icelandair
01 Oct - 14 Oct	Spirit Airlines
01 Oct - 08 Oct	jetBlue
21 Oct - 28 Oct	Turkish Airlines	direct

Also check the deals for one-way flights from Boston to Istanbul in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Boston to Istanbul in October from $384

Return flights