AirHint found the following cheapest return flights from Boston (BOS) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

07 Dec - 10 Dec	Spirit Airlines
06 Dec - 10 Dec	Spirit Airlines
10 Dec - 10 Dec	Spirit Airlines
06 Dec - 15 Dec	Spirit Airlines
07 Dec - 15 Dec	Spirit Airlines
10 Dec - 15 Dec	Spirit Airlines
03 Dec - 15 Dec	Spirit Airlines
15 Dec - 08 Jan	Spirit Airlines
13 Dec - 09 Jan	American Airlines
19 Dec - 09 Jan	Copa
20 Dec - 18 Jan	Spirit Airlines
29 Dec - 03 Jan	Spirit Airlines
20 Dec - 11 Jan	Spirit Airlines
15 Dec - 15 Dec	Spirit Airlines
29 Dec - 08 Jan	Spirit Airlines
19 Dec - 08 Jan	Spirit Airlines
29 Dec - 09 Jan	Spirit Airlines
20 Dec - 08 Jan	Spirit Airlines

Also check the deals for one-way flights from Boston to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Boston to Rio Negro in December from $319

Return flights