AirHint found the following cheapest return flights from Brussels (BRU) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

09 Sep - 16 Sep	Delta
09 Sep - 30 Sep	Delta
12 Sep - 30 Sep	Delta
17 Sep - 30 Sep	Delta
16 Sep - 29 Sep	Delta
11 Sep - 21 Sep	Delta
03 Sep - 26 Sep	Delta
02 Sep - 10 Sep	Delta
20 Sep - 28 Sep	Delta
02 Sep - 28 Sep	Delta
05 Sep - 15 Oct	Delta
02 Sep - 07 Oct	Delta
02 Sep - 08 Oct	Delta
03 Sep - 08 Oct	Delta
26 Sep - 19 Oct	Delta
15 Sep - 06 Oct	Delta
23 Sep - 03 Oct	Ryanair
26 Sep - 03 Oct	Delta
30 Sep - 05 Oct	Vueling Airlines
21 Sep - 10 Oct	Lufthansa

Also check the deals for one-way flights from Brussels to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Brussels to Sao Paulo in September from $740

Return flights