AirHint found the following cheapest return flights from Brussels (BRU) to Istanbul (IST) in May 2026 (see full year).

Return flights

10 May - 17 May	Aegean Airlines
22 May - 27 May	Aegean Airlines
01 May - 07 May	Wizz Air Malta
03 May - 23 May	Aegean Airlines
22 May - 27 May	Turkish Airlines	direct
01 May - 03 Jun	Turkish Airlines	direct
01 May - 07 May	Turkish Airlines	direct
03 May - 23 May	Turkish Airlines	direct
10 May - 17 May	Turkish Airlines	direct
01 May - 01 May	Turkish Airlines
01 May - 01 May	Turkish Airlines	direct

Also check the deals for one-way flights from Brussels to Istanbul in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Brussels to Istanbul in May from $255

Return flights