AirHint found the following cheapest return flights from Brussels (BRU) to Istanbul (IST) in September 2025 (see full year).

Return flights

03 Sep - 10 Sep	Wizz Air
01 Sep - 03 Sep	Wizz Air
21 Sep - 23 Sep	Wizz Air Malta
15 Sep - 23 Sep	Wizz Air
21 Sep - 24 Sep	Wizz Air Malta
22 Sep - 24 Sep	Wizz Air
15 Sep - 18 Sep	Wizz Air
03 Sep - 19 Sep	Wizz Air
09 Sep - 30 Sep	Pegasus Airlines
22 Sep - 30 Sep	Wizz Air
30 Sep - 11 Oct	Wizz Air
29 Sep - 08 Oct	Wizz Air
28 Sep - 09 Oct	AJet
30 Sep - 04 Oct	Wizz Air
28 Sep - 09 Oct	AJet	direct
26 Sep - 02 Oct	Pegasus Airlines	direct
20 Sep - 11 Oct	AJet	direct
29 Sep - 08 Oct	AJet	direct
27 Sep - 03 Oct	AJet	direct
30 Sep - 11 Oct	Pegasus Airlines	direct

Also check the deals for one-way flights from Brussels to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Brussels to Istanbul in September from $149

Return flights