AirHint found the following cheapest return flights from Brussels (BRU) to Santo Domingo (SDQ) in September 2025 (see full year).

Return flights

25 Sep - 12 Oct	Air Europa
24 Sep - 08 Oct	Air Europa
24 Sep - 05 Oct	Air Europa
27 Sep - 11 Oct	Air Europa
06 Sep - 21 Sep	Iberia
11 Sep - 24 Sep	Air Europa
08 Sep - 21 Sep	Air Europa
03 Sep - 17 Sep	Iberia
01 Sep - 06 Sep	Air Europa
08 Sep - 17 Sep	Iberia
01 Sep - 10 Sep	TAP
01 Sep - 11 Sep	Air Europa
02 Sep - 16 Sep	Air Europa
02 Sep - 10 Sep	Delta

Also check the deals for one-way flights from Brussels to Santo Domingo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Brussels to Santo Domingo in September from $579

Return flights