AirHint found the following cheapest return flights from Brussels (BRU) to Santander (SDR) in December 2025 (see full year).

Return flights

13 Dec - 31 Dec	Ryanair	direct
13 Dec - 27 Dec	Ryanair
08 Dec - 27 Dec	Ryanair
06 Dec - 27 Dec	Ryanair
07 Dec - 27 Dec	Vueling Airlines
13 Dec - 27 Dec	Ryanair	direct
08 Dec - 27 Dec	Ryanair	direct
19 Dec - 02 Jan	Vueling Airlines
20 Dec - 03 Jan	Vueling Airlines

Also check the deals for one-way flights from Brussels to Santander in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Brussels to Santander in December from $99

Return flights