AirHint found the following cheapest return flights from Cairo (CAI) to Prague (PRG) in October 2025 (see full year).

Return flights

07 Oct - 09 Oct	SWISS
09 Oct - 14 Oct	SWISS
06 Oct - 14 Oct	SWISS
10 Oct - 20 Oct	SWISS
16 Oct - 21 Oct	SWISS
07 Oct - 12 Oct	SWISS
06 Oct - 11 Oct	SWISS
06 Oct - 12 Oct	SWISS
04 Oct - 07 Oct	SWISS
04 Oct - 09 Oct	SWISS
26 Oct - 04 Nov	EgyptAir	direct
28 Oct - 04 Nov	EgyptAir	direct
30 Oct - 03 Nov	AJet
23 Oct - 10 Nov	Vueling Airlines
23 Oct - 08 Nov	Vueling Airlines
23 Oct - 06 Nov	Vueling Airlines
20 Oct - 08 Nov	Vueling Airlines
14 Oct - 01 Nov	Vueling Airlines
20 Oct - 06 Nov	Vueling Airlines
28 Oct - 10 Nov	Vueling Airlines

Also check the deals for one-way flights from Cairo to Prague in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cairo to Prague in October from $233

Return flights