AirHint found the following cheapest return flights from Cairo (CAI) to Prague (PRG) in December 2025 (see full year).

Return flights

05 Dec - 12 Dec	SWISS
04 Dec - 11 Dec	LOT
26 Dec - 30 Dec	Lufthansa
28 Dec - 01 Jan	LOT
30 Dec - 06 Jan	LOT
29 Dec - 05 Jan	LOT
18 Dec - 25 Dec	LOT
28 Dec - 01 Jan	EgyptAir	direct
30 Dec - 06 Jan	EgyptAir	direct
04 Dec - 11 Dec	EgyptAir	direct
18 Dec - 25 Dec	EgyptAir	direct
25 Dec - 10 Jan	Vueling Airlines
20 Dec - 10 Jan	Vueling Airlines
27 Dec - 10 Jan	Vueling Airlines
25 Dec - 05 Jan	Vueling Airlines
18 Dec - 05 Jan	Vueling Airlines
04 Dec - 06 Dec	Vueling Airlines
06 Dec - 25 Dec	Vueling Airlines
13 Dec - 25 Dec	Vueling Airlines
20 Dec - 25 Dec	Vueling Airlines

Also check the deals for one-way flights from Cairo to Prague in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cairo to Prague in December from $262

Return flights