AirHint found the following cheapest return flights from Cairo (CAI) to Prague (PRG) in September 2025 (see full year).

Return flights

19 Sep - 24 Sep	LOT
30 Sep - 05 Oct	LOT
19 Sep - 23 Sep	LOT
22 Sep - 29 Sep	LOT
26 Sep - 29 Sep	LOT
15 Sep - 18 Sep	LOT
18 Sep - 22 Sep	LOT
28 Sep - 03 Oct	Lufthansa
25 Sep - 28 Sep	Austrian Airlines
25 Sep - 27 Sep	Austrian Airlines
27 Sep - 01 Oct	Austrian Airlines
21 Sep - 24 Sep	Transavia France
23 Sep - 25 Sep	SWISS
28 Sep - 05 Oct	Lufthansa
30 Sep - 05 Oct	EgyptAir	direct
30 Sep - 15 Oct	Vueling Airlines
30 Sep - 13 Oct	Vueling Airlines
29 Sep - 06 Oct	Vueling Airlines
27 Sep - 06 Oct	Vueling Airlines
29 Sep - 15 Oct	Vueling Airlines

Also check the deals for one-way flights from Cairo to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague

Cheapest return flights from Cairo to Prague in September from $262

Return flights