AirHint found the following cheapest return flights from Cairo (CAI) to Prague (PRG) in September 2025 (see full year).

Return flights

18 Sep - 25 Sep	SWISS
09 Sep - 11 Sep	SWISS
18 Sep - 22 Sep	SWISS
15 Sep - 22 Sep	SWISS
16 Sep - 23 Sep	SWISS
09 Sep - 18 Sep	SWISS
11 Sep - 18 Sep	SWISS
12 Sep - 19 Sep	SWISS
18 Sep - 24 Sep	SWISS
21 Sep - 25 Sep	Lufthansa
25 Sep - 01 Oct	Vueling Airlines
18 Sep - 01 Oct	Vueling Airlines
25 Sep - 13 Oct	Vueling Airlines
15 Sep - 01 Oct	Vueling Airlines
16 Sep - 01 Oct	Vueling Airlines
25 Sep - 12 Oct	Vueling Airlines

Also check the deals for one-way flights from Cairo to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cairo to Prague in September from $228

Return flights