Cheapest return flights from Rome to Istanbul in October from $162

Best time to book flights for Rome (CIA) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest return flights from Rome (CIA) to Istanbul (IST) in October 2025 (see full year).

Return flights

02 Oct - 08 Oct Ryanair
01 Oct - 05 Nov Ryanair
01 Oct - 08 Oct Ryanair
01 Oct - 07 Oct Ryanair
01 Oct - 14 Oct Ryanair
01 Oct - 11 Oct Ryanair
02 Oct - 09 Oct Ryanair
01 Oct - 09 Oct Ryanair
02 Oct - 07 Oct Ryanair
07 Oct - 11 Oct Ryanair
08 Oct - 11 Oct Ryanair
25 Oct - 02 Nov Ryanair
11 Oct - 01 Nov Ryanair
31 Oct - 05 Nov Ryanair
25 Oct - 01 Nov Ryanair
29 Oct - 07 Nov Ryanair
31 Oct - 03 Nov Ryanair
30 Oct - 02 Nov Ryanair
30 Oct - 03 Nov Ryanair

Also check the deals for one-way flights from Rome to Istanbul in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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