AirHint found the following cheapest return flights from Rome (CIA) to Panama City (PTY) in December 2025 (see full year).
Return flights
| 05 Dec - 11 Dec | Ryanair | ||
| 26 Dec - 05 Jan | Ryanair | ||
| 27 Dec - 06 Jan | Ryanair | ||
| 23 Dec - 31 Dec | Ryanair | ||
| 27 Dec - 07 Jan | Ryanair | ||
| 15 Dec - 07 Jan | Ryanair | ||
| 18 Dec - 02 Jan | Ryanair |
Also check the deals for one-way flights from Rome to Panama City in December.
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