Cheapest return flights from Cali to Guayaquil in December from $379

AirHint found the following cheapest return flights from Cali (CLO) to Guayaquil (GYE) in December 2025 (see full year).

Return flights

21 Dec - 20 Jan Copa
15 Dec - 22 Dec Copa

Also check the deals for one-way flights from Cali to Guayaquil in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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