AirHint found the following cheapest return flights from Cali (CLO) to Madrid (MAD) in October 2025 (see full year).

Return flights

08 Oct - 29 Oct	JetSmart
21 Oct - 05 Nov	Avianca
22 Oct - 05 Nov	Avianca
28 Oct - 06 Nov	Avianca
30 Oct - 06 Nov	Avianca
24 Oct - 02 Nov	JetSmart
30 Oct - 17 Nov	Avianca
31 Oct - 17 Nov	Avianca
15 Oct - 05 Nov	Avianca
11 Oct - 11 Nov	Spirit Airlines
11 Oct - 14 Nov	Spirit Airlines
16 Oct - 31 Oct	Avianca
14 Oct - 31 Oct	Avianca
10 Oct - 31 Oct	Avianca
17 Oct - 31 Oct	Avianca
20 Oct - 27 Oct	JetSmart
15 Oct - 31 Oct	Avianca
11 Oct - 26 Oct	Spirit Airlines
11 Oct - 18 Oct	Spirit Airlines
24 Oct - 26 Oct	Avianca

Also check the deals for one-way flights from Cali to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cali to Madrid in October from $778

Return flights