AirHint found the following cheapest return flights from Cali (CLO) to Madrid (MAD) in September 2025 (see full year).

Return flights

30 Sep - 16 Oct	Avianca
29 Sep - 21 Oct	LATAM Airlines Group
23 Sep - 07 Oct	Avianca
22 Sep - 07 Oct	Avianca
29 Sep - 28 Oct	LATAM Airlines Group
28 Sep - 29 Oct	Copa
28 Sep - 19 Oct	LATAM Airlines Group
30 Sep - 23 Oct	LATAM Airlines Group
23 Sep - 15 Oct	Wingo
28 Sep - 25 Oct	LATAM Airlines Group
22 Sep - 29 Sep	Avianca
22 Sep - 28 Sep	Avianca
21 Sep - 29 Sep	Avianca
23 Sep - 30 Sep	Avianca
22 Sep - 30 Sep	Avianca
21 Sep - 28 Sep	JetSmart
22 Sep - 27 Sep	Avianca
23 Sep - 27 Sep	Avianca
21 Sep - 30 Sep	Avianca
22 Sep - 26 Sep	Avianca

Also check the deals for one-way flights from Cali to Madrid in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cali to Madrid in September from $895

Return flights