AirHint found the following cheapest return flights from Cali (CLO) to Madrid (MAD) in September 2025 (see full year).

Return flights

05 Sep - 21 Sep	Spirit Airlines
24 Sep - 08 Oct	Spirit Airlines
01 Sep - 15 Sep	JetSmart
01 Sep - 14 Sep	JetSmart
24 Sep - 08 Oct	WORLD2FLY	direct
15 Sep - 24 Sep	Avianca
16 Sep - 02 Oct	Avianca
25 Sep - 14 Oct	Wingo
08 Sep - 17 Sep	Wingo
24 Sep - 22 Oct	LATAM Airlines Group
24 Sep - 15 Oct	WORLD2FLY	direct
28 Sep - 12 Oct	WORLD2FLY	direct
13 Sep - 23 Sep	Avianca
26 Sep - 12 Oct	Avianca
12 Sep - 17 Sep	Avianca
12 Sep - 19 Sep	Avianca
30 Sep - 31 Oct	Avianca
10 Sep - 24 Sep	Avianca
25 Sep - 31 Oct	Avianca
11 Sep - 25 Sep	Avianca

Also check the deals for one-way flights from Cali to Madrid in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cali to Madrid in September from $796

Return flights