AirHint found the following cheapest return flights from Cali (CLO) to Mexico City (MEX) in December 2025 (see full year).

Return flights

12 Dec - 11 Jan	Aeromexico	direct
02 Dec - 15 Jan	Copa
12 Dec - 24 Jan	Copa
02 Dec - 15 Jan	Aeromexico	direct
12 Dec - 24 Jan	Aeromexico	direct
21 Dec - 29 Dec	Aeromexico	direct
24 Dec - 06 Jan	Aeromexico
01 Dec - 06 Dec	Aeromexico	direct
06 Dec - 12 Dec	Avianca
22 Dec - 10 Jan	Aeromexico
21 Dec - 11 Jan	Avianca
27 Dec - 13 Jan	Copa
20 Dec - 04 Jan	Avianca
14 Dec - 27 Dec	Copa
12 Dec - 18 Dec	Avianca
05 Dec - 12 Dec	Avianca
05 Dec - 11 Dec	Avianca
20 Dec - 29 Dec	Avianca
14 Dec - 29 Dec	Avianca
12 Dec - 29 Dec	Avianca

Also check the deals for one-way flights from Cali to Mexico City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cali to Mexico City in December from $280

Return flights