AirHint found the following cheapest return flights from Charlotte (CLT) to Guatemala City (GUA) in October 2025 (see full year).

Return flights

06 Oct - 21 Oct	Spirit Airlines
14 Oct - 21 Oct	Spirit Airlines
06 Oct - 18 Oct	Spirit Airlines
14 Oct - 18 Oct	Spirit Airlines
29 Oct - 08 Nov	Spirit Airlines
08 Oct - 21 Oct	Spirit Airlines
02 Oct - 21 Oct	Spirit Airlines
09 Oct - 21 Oct	Spirit Airlines
08 Oct - 18 Oct	Spirit Airlines
02 Oct - 18 Oct	Spirit Airlines
09 Oct - 18 Oct	Spirit Airlines
19 Oct - 08 Nov	Spirit Airlines

Also check the deals for one-way flights from Charlotte to Guatemala City in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Charlotte to Guatemala City in October from $266

Return flights