AirHint found the following cheapest return flights from Columbus (CMH) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

09 Sep - 15 Sep	Spirit Airlines
03 Sep - 17 Sep	Spirit Airlines
09 Sep - 23 Sep	Spirit Airlines
09 Sep - 30 Sep	Spirit Airlines
09 Sep - 24 Sep	Spirit Airlines
02 Sep - 23 Sep	Spirit Airlines
03 Sep - 24 Sep	Spirit Airlines
24 Sep - 15 Oct	Spirit Airlines
10 Sep - 01 Oct	Spirit Airlines
02 Sep - 16 Sep	Spirit Airlines
16 Sep - 27 Sep	Spirit Airlines
16 Sep - 07 Oct	Spirit Airlines
30 Sep - 21 Oct	Spirit Airlines
16 Sep - 24 Sep	Spirit Airlines
23 Sep - 14 Oct	Spirit Airlines
17 Sep - 08 Oct	Spirit Airlines

Also check the deals for one-way flights from Columbus to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Columbus to Sao Paulo in September from $480

Return flights