AirHint found the following cheapest return flights from Columbus (CMH) to Rio Negro (MDE) in April 2026 (see full year).

Return flights

07 Apr - 14 Apr	Spirit Airlines
08 Apr - 14 Apr	Spirit Airlines
11 Apr - 14 Apr	Spirit Airlines
07 Apr - 08 Apr	Spirit Airlines
07 Apr - 21 Apr	Spirit Airlines
14 Apr - 21 Apr	Spirit Airlines
15 Apr - 22 Apr	Spirit Airlines
13 Apr - 20 Apr	Allegiant Air
08 Apr - 22 Apr	Spirit Airlines
22 Apr - 06 May	Spirit Airlines
28 Apr - 19 May	Spirit Airlines
07 Apr - 11 Apr	Spirit Airlines
21 Apr - 05 May	Spirit Airlines
29 Apr - 19 May	Spirit Airlines
29 Apr - 20 May	Spirit Airlines
25 Apr - 02 May	Spirit Airlines

Also check the deals for one-way flights from Columbus to Rio Negro in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Columbus to Rio Negro in April from $242

Return flights