AirHint found the following cheapest return flights from Cartagena (CTG) to Santiago (SCL) in October 2025 (see full year).

Return flights

05 Oct - 26 Oct	JetSmart
06 Oct - 26 Oct	JetSmart
23 Oct - 26 Oct	JetSmart
06 Oct - 27 Oct	JetSmart
23 Oct - 27 Oct	JetSmart
16 Oct - 26 Oct	JetSmart
16 Oct - 27 Oct	JetSmart
05 Oct - 23 Oct	JetSmart
05 Oct - 17 Oct	JetSmart
05 Oct - 24 Oct	JetSmart
23 Oct - 03 Nov	JetSmart
23 Oct - 10 Nov	JetSmart
27 Oct - 16 Nov	JetSmart
16 Oct - 03 Nov	JetSmart
27 Oct - 03 Nov	JetSmart
27 Oct - 10 Nov	JetSmart
13 Oct - 03 Nov	JetSmart
24 Oct - 03 Nov	JetSmart
24 Oct - 10 Nov	JetSmart

Also check the deals for one-way flights from Cartagena to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cartagena to Santiago in October from $355

Return flights