AirHint found the following cheapest return flights from Cartagena (CTG) to Santiago (SCL) in December 2025 (see full year).

Return flights

07 Dec - 15 Dec	JetSmart
07 Dec - 08 Dec	JetSmart
08 Dec - 15 Dec	JetSmart
14 Dec - 15 Dec	JetSmart
03 Dec - 15 Dec	JetSmart
03 Dec - 08 Dec	JetSmart
10 Dec - 15 Dec	JetSmart
12 Dec - 15 Dec	JetSmart
07 Dec - 11 Dec	JetSmart
08 Dec - 11 Dec	JetSmart
14 Dec - 04 Jan	JetSmart
15 Dec - 04 Jan	JetSmart
14 Dec - 02 Jan	JetSmart
18 Dec - 07 Jan	JetSmart
28 Dec - 14 Jan	JetSmart
15 Dec - 02 Jan	JetSmart
14 Dec - 03 Jan	JetSmart
12 Dec - 02 Jan	JetSmart
18 Dec - 04 Jan	JetSmart
15 Dec - 05 Jan	JetSmart

Also check the deals for one-way flights from Cartagena to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago

Cheapest return flights from Cartagena to Santiago in December from $328

Return flights