AirHint found the following cheapest return flights from Cancun (CUN) to Guatemala City (GUA) in September 2025 (see full year).

Return flights

24 Sep - 02 Oct	Aeromexico
12 Sep - 17 Sep	Volaris El Salvador	direct
24 Sep - 30 Sep	Copa
23 Sep - 01 Oct	Copa
24 Sep - 01 Oct	Copa
17 Sep - 23 Sep	Aeromexico
22 Sep - 25 Sep	Aeromexico
22 Sep - 24 Sep	Aeromexico
11 Sep - 18 Sep	Aeromexico
13 Sep - 14 Sep	Aeromexico
14 Sep - 15 Sep	Aeromexico
15 Sep - 21 Sep	Aeromexico
20 Sep - 27 Sep	Aeromexico
09 Sep - 06 Oct	Aeromexico

Also check the deals for one-way flights from Cancun to Guatemala City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cancun to Guatemala City in September from $214

Return flights