AirHint found the following cheapest return flights from Cancun (CUN) to Rio Negro (MDE) in October 2025 (see full year).

Return flights

23 Oct - 26 Oct	Avianca
18 Oct - 03 Nov	Copa
22 Oct - 04 Nov	Copa
18 Oct - 24 Oct	Copa
07 Oct - 13 Oct	Copa
07 Oct - 14 Oct	Copa
17 Oct - 20 Oct	Copa
18 Oct - 25 Oct	Copa
01 Oct - 11 Oct	Copa
29 Oct - 07 Nov	Copa
16 Oct - 18 Oct	Copa
23 Oct - 28 Oct	Copa
17 Oct - 26 Oct	Copa
28 Oct - 04 Nov	Copa
30 Oct - 04 Nov	Copa
23 Oct - 03 Nov	Viva
23 Oct - 04 Nov	Viva
23 Oct - 09 Nov	Viva
16 Oct - 03 Nov	Viva
16 Oct - 04 Nov	Viva

Also check the deals for one-way flights from Cancun to Rio Negro in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cancun to Rio Negro in October from $273

Return flights