AirHint found the following cheapest return flights from Cancun (CUN) to Rio Negro (MDE) in April 2026 (see full year).

Return flights

20 Apr - 03 May	Aeromexico
15 Apr - 19 Apr	Aeromexico
18 Apr - 26 Apr	Aeromexico
09 Apr - 29 Apr	Copa
02 Apr - 09 Apr	Copa
02 Apr - 18 Apr	Copa
09 Apr - 14 Apr	Copa
01 Apr - 07 Apr	Copa
03 Apr - 07 Apr	Copa
06 Apr - 10 Apr	Copa
11 Apr - 17 Apr	Copa
20 Apr - 03 May	Avianca	direct

Also check the deals for one-way flights from Cancun to Rio Negro in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cancun to Rio Negro in April from $291

Return flights