AirHint found the following cheapest return flights from Cancun (CUN) to Rio Negro (MDE) in September 2026 (see full year).

Return flights

06 Sep - 10 Sep	Copa
11 Sep - 16 Sep	Copa
17 Sep - 19 Sep	Copa
13 Sep - 17 Sep	Copa
13 Sep - 19 Sep	Copa
19 Sep - 22 Sep	Copa
07 Sep - 10 Sep	Copa
23 Sep - 04 Oct	Copa
06 Sep - 22 Sep	Viva
07 Sep - 22 Sep	Viva
13 Sep - 22 Sep	Viva
19 Sep - 06 Oct	Viva
14 Sep - 05 Oct	Viva
23 Sep - 04 Oct	Avianca	direct
19 Sep - 05 Oct	Viva

Also check the deals for one-way flights from Cancun to Rio Negro in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cancun to Rio Negro in September from $345

Return flights