AirHint found the following cheapest return flights from Cancun (CUN) to Panama City (PTY) in September 2025 (see full year).

Return flights

04 Sep - 11 Sep	Avianca
12 Sep - 15 Sep	Avianca
12 Sep - 17 Sep	Avianca
19 Sep - 21 Sep	Aeromexico
19 Sep - 22 Sep	Aeromexico
04 Sep - 11 Sep	Copa	direct
12 Sep - 15 Sep	Copa	direct
12 Sep - 17 Sep	Copa	direct
11 Sep - 16 Sep	Copa	direct
19 Sep - 21 Sep	Copa	direct

Also check the deals for one-way flights from Cancun to Panama City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cancun to Panama City in September from $245

Return flights