AirHint found the following cheapest return flights from Cancun (CUN) to Santiago (SCL) in December 2025 (see full year).

Return flights

04 Dec - 13 Dec	Sky Airline
04 Dec - 12 Dec	Sky Airline
13 Dec - 20 Dec	Sky Airline
08 Dec - 17 Dec	Copa
05 Dec - 14 Dec	Copa
11 Dec - 06 Jan	Sky Airline
09 Dec - 30 Dec	Arajet
20 Dec - 12 Jan	Sky Airline
18 Dec - 08 Jan	Sky Airline
23 Dec - 29 Dec	Arajet
20 Dec - 10 Jan	Sky Airline
26 Dec - 10 Jan	LATAM Airlines Group
19 Dec - 29 Dec	Copa
19 Dec - 09 Jan	Copa
16 Dec - 31 Dec	LATAM Airlines Group
21 Dec - 04 Jan	Copa

Also check the deals for one-way flights from Cancun to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cancun to Santiago in December from $426

Return flights