AirHint found the following cheapest return flights from Cuzco (CUZ) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

13 Dec - 19 Dec	JetSmart
03 Dec - 12 Dec	JetSmart
06 Dec - 12 Dec	JetSmart
13 Dec - 26 Dec	JetSmart
05 Dec - 12 Dec	JetSmart
03 Dec - 19 Dec	JetSmart
13 Dec - 28 Dec	JetSmart
06 Dec - 19 Dec	JetSmart
09 Dec - 12 Dec	JetSmart
05 Dec - 19 Dec	JetSmart
13 Dec - 02 Jan	JetSmart
24 Dec - 11 Jan	JetSmart
24 Dec - 02 Jan	JetSmart
16 Dec - 02 Jan	JetSmart
31 Dec - 11 Jan	JetSmart
20 Dec - 02 Jan	JetSmart
31 Dec - 02 Jan	JetSmart
19 Dec - 02 Jan	JetSmart
27 Dec - 11 Jan	JetSmart
27 Dec - 02 Jan	JetSmart

Also check the deals for one-way flights from Cuzco to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rio Negro

Cheap car rent in Rio Negro

Cheapest return flights from Cuzco to Rio Negro in December from $313

Return flights