AirHint found the following cheapest return flights from Cuzco (CUZ) to Rio Negro (MDE) in September 2025 (see full year).

Return flights

07 Sep - 23 Sep	JetSmart
07 Sep - 13 Sep	JetSmart
06 Sep - 23 Sep	JetSmart
10 Sep - 23 Sep	JetSmart
10 Sep - 13 Sep	JetSmart
14 Sep - 23 Sep	JetSmart
06 Sep - 13 Sep	JetSmart
15 Sep - 23 Sep	JetSmart
18 Sep - 23 Sep	JetSmart
06 Sep - 07 Sep	JetSmart
18 Sep - 07 Oct	JetSmart
29 Sep - 07 Oct	JetSmart
17 Sep - 07 Oct	JetSmart
29 Sep - 15 Oct	JetSmart
29 Sep - 10 Oct	JetSmart

Also check the deals for one-way flights from Cuzco to Rio Negro in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cuzco to Rio Negro in September from $257

Return flights