AirHint found the following cheapest return flights from Cuzco (CUZ) to Santiago (SCL) in September 2025 (see full year).

Return flights

04 Sep - 24 Sep	JetSmart
04 Sep - 22 Sep	JetSmart
04 Sep - 25 Sep	JetSmart
04 Sep - 21 Sep	JetSmart
04 Sep - 19 Sep	JetSmart
04 Sep - 23 Sep	JetSmart
04 Sep - 10 Sep	JetSmart
04 Sep - 08 Sep	JetSmart
04 Sep - 06 Sep	JetSmart
04 Sep - 20 Sep	JetSmart
30 Sep - 11 Oct	JetSmart
30 Sep - 21 Oct	JetSmart
25 Sep - 11 Oct	JetSmart
30 Sep - 19 Oct	JetSmart
30 Sep - 03 Oct	JetSmart
30 Sep - 06 Oct	JetSmart
30 Sep - 13 Oct	JetSmart
30 Sep - 08 Oct	JetSmart
30 Sep - 15 Oct	JetSmart
30 Sep - 02 Oct	JetSmart

Also check the deals for one-way flights from Cuzco to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cuzco to Santiago in September from $220

Return flights