AirHint found the following cheapest return flights from Detroit (DTW) to Cairo (CAI) in December 2025 (see full year).

Return flights

02 Dec - 15 Jan	Delta
09 Dec - 16 Dec	Delta
10 Dec - 14 Dec	Air Canada
16 Dec - 16 Jan	KLM
24 Dec - 28 Dec	Air Canada
17 Dec - 09 Jan	KLM
15 Dec - 09 Jan	Air Canada
16 Dec - 30 Dec	jetBlue
23 Dec - 09 Jan	Air Canada
24 Dec - 09 Jan	Air Canada
25 Dec - 09 Jan	Air Canada
15 Dec - 02 Jan	Spirit Airlines
22 Dec - 09 Jan	Air Canada
19 Dec - 27 Dec	Spirit Airlines
19 Dec - 02 Jan	Spirit Airlines

Also check the deals for one-way flights from Detroit to Cairo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Detroit to Cairo in December from $722

Return flights