Cheapest return flights from Detroit to Rome in September from $515

AirHint found the following cheapest return flights from Detroit (DTW) to Rome (FCO) in September 2025 (see full year).

Return flights

15 Sep - 23 Sep Spirit Airlines
13 Sep - 16 Sep Frontier Airlines
26 Sep - 06 Oct Spirit Airlines
15 Sep - 22 Sep Spirit Airlines
22 Sep - 18 Oct Spirit Airlines
19 Sep - 09 Oct Frontier Airlines
24 Sep - 18 Oct Spirit Airlines
30 Sep - 12 Oct Spirit Airlines
05 Sep - 13 Sep Condor
24 Sep - 29 Sep Spirit Airlines
23 Sep - 29 Sep Spirit Airlines
10 Sep - 25 Sep Spirit Airlines
13 Sep - 20 Sep Frontier Airlines
14 Sep - 17 Sep Spirit Airlines
30 Sep - 25 Oct Spirit Airlines
08 Sep - 14 Sep Frontier Airlines
17 Sep - 11 Oct Spirit Airlines
30 Sep - 07 Oct United
30 Sep - 25 Oct Air France direct
24 Sep - 01 Oct United

Also check the deals for one-way flights from Detroit to Rome in September.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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