Cheapest return flights from Detroit to Rome in September from $643

Best time to book flights for Detroit (DTW) to Rome (FCO) flights at AirHint

AirHint found the following cheapest return flights from Detroit (DTW) to Rome (FCO) in September 2025 (see full year).

Return flights

30 Sep - 07 Oct Scandinavian Airlines
10 Sep - 24 Sep Turkish Airlines
12 Sep - 30 Sep Turkish Airlines
22 Sep - 29 Sep Turkish Airlines
06 Sep - 26 Sep Turkish Airlines
18 Sep - 28 Sep Turkish Airlines
08 Sep - 20 Sep Turkish Airlines
01 Sep - 08 Sep Icelandair
30 Sep - 07 Oct Delta direct
22 Sep - 29 Sep Delta direct
26 Sep - 03 Oct United
21 Sep - 28 Sep United
18 Sep - 28 Sep Delta direct

Also check the deals for one-way flights from Detroit to Rome in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rome

Cheap car rent in Rome