AirHint found the following cheapest return flights from Detroit (DTW) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

05 Dec - 10 Dec	Frontier Airlines
03 Dec - 10 Dec	Spirit Airlines
04 Dec - 11 Dec	Frontier Airlines
14 Dec - 14 Jan	Frontier Airlines
23 Dec - 11 Jan	Frontier Airlines
14 Dec - 11 Jan	Spirit Airlines
20 Dec - 10 Jan	Spirit Airlines
26 Dec - 10 Jan	Frontier Airlines
20 Dec - 07 Jan	Spirit Airlines
13 Dec - 20 Dec	Spirit Airlines
20 Dec - 06 Jan	Spirit Airlines
18 Dec - 31 Dec	Spirit Airlines
19 Dec - 09 Jan	Frontier Airlines
18 Dec - 05 Jan	Spirit Airlines
20 Dec - 05 Jan	Spirit Airlines
20 Dec - 30 Dec	United

Also check the deals for one-way flights from Detroit to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Detroit to Sao Paulo in December from $630

Return flights