Cheapest return flights from Detroit to Istanbul in September from $702

AirHint found the following cheapest return flights from Detroit (DTW) to Istanbul (IST) in September 2025 (see full year).

Return flights

13 Sep - 16 Sep Frontier Airlines
28 Sep - 16 Oct Spirit Airlines
24 Sep - 04 Oct Spirit Airlines
11 Sep - 25 Sep Spirit Airlines
15 Sep - 11 Oct Spirit Airlines
16 Sep - 11 Oct Spirit Airlines
05 Sep - 12 Sep Frontier Airlines
19 Sep - 11 Oct Frontier Airlines
17 Sep - 26 Sep Spirit Airlines
21 Sep - 11 Oct Spirit Airlines
06 Sep - 31 Oct Spirit Airlines
26 Sep - 18 Oct Spirit Airlines
17 Sep - 27 Sep Spirit Airlines
05 Sep - 27 Sep Frontier Airlines
09 Sep - 04 Oct Spirit Airlines
14 Sep - 19 Sep Spirit Airlines
12 Sep - 28 Sep Frontier Airlines
03 Sep - 12 Sep Spirit Airlines
28 Sep - 16 Oct Turkish Airlines direct
07 Sep - 11 Sep Alaska Airlines

Also check the deals for one-way flights from Detroit to Istanbul in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Istanbul

Cheap car rent in Istanbul

Feel free to contact us with any feedback or request another flight research.