AirHint found the following cheapest return flights from Duesseldorf (DUS) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

08 Dec - 24 Dec	Air France
14 Dec - 17 Jan	ITA Airways
11 Dec - 14 Dec	KLM
30 Dec - 17 Jan	TAP
26 Dec - 25 Jan	KLM
10 Dec - 17 Dec	KLM
16 Dec - 30 Dec	ITA Airways
14 Dec - 30 Dec	ITA Airways
26 Dec - 23 Jan	KLM
10 Dec - 30 Dec	KLM
26 Dec - 16 Jan	ITA Airways
13 Dec - 30 Dec	KLM
11 Dec - 18 Dec	KLM
12 Dec - 19 Dec	KLM
29 Dec - 11 Jan	ITA Airways
11 Dec - 30 Dec	KLM
09 Dec - 01 Jan	KLM
31 Dec - 16 Jan	Lufthansa
25 Dec - 10 Jan	TAP
25 Dec - 07 Jan	TAP

Also check the deals for one-way flights from Duesseldorf to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Duesseldorf to Sao Paulo in December from $1184

Return flights