AirHint found the following cheapest return flights from Duesseldorf (DUS) to Prague (PRG) in October 2025 (see full year).

Return flights

19 Oct - 21 Oct	Eurowings	direct
01 Oct - 02 Oct	easyJet
12 Oct - 21 Oct	Eurowings	direct
15 Oct - 21 Oct	Eurowings	direct
06 Oct - 09 Oct	easyJet
19 Oct - 22 Oct	Eurowings	direct
06 Oct - 09 Oct	Eurowings	direct
26 Oct - 31 Oct	Eurowings	direct
25 Oct - 01 Nov	easyJet
18 Oct - 23 Oct	easyJet
06 Oct - 08 Oct	Eurowings	direct
26 Oct - 02 Nov	easyJet
31 Oct - 02 Nov	easyJet
31 Oct - 03 Nov	Eurowings	direct
29 Oct - 02 Nov	Eurowings
26 Oct - 02 Nov	Eurowings	direct
31 Oct - 02 Nov	Eurowings	direct

Also check the deals for one-way flights from Duesseldorf to Prague in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Duesseldorf to Prague in October from $139

Return flights