AirHint found the following cheapest return flights from Duesseldorf (DUS) to Prague (PRG) in December 2025 (see full year).

Return flights

07 Dec - 10 Dec	easyJet
03 Dec - 05 Dec	easyJet
03 Dec - 05 Dec	Eurowings	direct
07 Dec - 10 Dec	Eurowings	direct
18 Dec - 22 Dec	easyJet
11 Dec - 14 Dec	easyJet
24 Dec - 28 Dec	Eurowings	direct
22 Dec - 26 Dec	Eurowings	direct
30 Dec - 01 Jan	Eurowings	direct
04 Dec - 07 Dec	easyJet
18 Dec - 22 Dec	Eurowings	direct
30 Dec - 03 Jan	Eurowings	direct
30 Dec - 02 Jan	Eurowings	direct
27 Dec - 01 Jan	Eurowings	direct
31 Dec - 03 Jan	easyJet
31 Dec - 03 Jan	Eurowings	direct
29 Dec - 02 Jan	KLM
31 Dec - 04 Jan	LOT
29 Dec - 03 Jan	KLM
30 Dec - 04 Jan	LOT

Also check the deals for one-way flights from Duesseldorf to Prague in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Duesseldorf to Prague in December from $166

Return flights