AirHint found the following cheapest return flights from Duesseldorf (DUS) to Prague (PRG) in April 2026 (see full year).

Return flights

14 Apr - 18 Apr	Ryanair
22 Apr - 24 Apr	Eurowings	direct
13 Apr - 16 Apr	easyJet
29 Apr - 01 May	Eurowings	direct
13 Apr - 18 Apr	Ryanair
18 Apr - 24 Apr	Ryanair
19 Apr - 27 Apr	Eurowings	direct
22 Apr - 25 Apr	Eurowings
28 Apr - 30 Apr	Eurowings	direct
12 Apr - 18 Apr	Eurowings	direct
21 Apr - 25 Apr	Eurowings
28 Apr - 02 May	Eurowings	direct
29 Apr - 02 May	Eurowings	direct
30 Apr - 04 May	Eurowings	direct
30 Apr - 03 May	Lufthansa
30 Apr - 03 May	Eurowings	direct

Also check the deals for one-way flights from Duesseldorf to Prague in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Duesseldorf to Prague in April from $138

Return flights