AirHint found the following cheapest return flights from Duesseldorf (DUS) to Prague (PRG) in September 2025 (see full year).

Return flights

09 Sep - 11 Sep	Eurowings
09 Sep - 10 Sep	Eurowings	direct
14 Sep - 19 Sep	Eurowings	direct
16 Sep - 23 Sep	easyJet
21 Sep - 27 Sep	Eurowings	direct
04 Sep - 26 Sep	Eurowings	direct
01 Sep - 03 Sep	easyJet
04 Sep - 09 Sep	Eurowings	direct
02 Sep - 04 Sep	easyJet
01 Sep - 04 Sep	easyJet
29 Sep - 04 Oct	easyJet
30 Sep - 05 Oct	easyJet
29 Sep - 04 Oct	Eurowings	direct
30 Sep - 05 Oct	Eurowings	direct

Also check the deals for one-way flights from Duesseldorf to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Duesseldorf to Prague in September from $131

Return flights